| ANTIBODY PHOTO | MART-1 Cocktail | |
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MART-1 Cocktail Description This is a cocktail of two MART-1 (Melanoma Associated Antigen Recognized by T-cells) antibodies with different epitopes. The MART-1/Melan A recognizes a protein of 18kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. The MART-1 recognizes a subcellular fraction found in melanosomes. The antibody labels melanomas and tumors showing melanocytic differentiation. It does not mark neoplasms of epithelial origin, lymphomas or mesenchymal tumors. Melan-A is a useful addition to melanoma panels which are specific to melanocytic lesions. Both HMB-45 and MART-1 are coexpressed in the majority of melanomas, as well as solely expressed in certain cases. Studies have shown that MART-1 is more sensitive than HMB-45 when labeling metastatic melanomas. |
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| PHOTO DESC. | Cat No. | |
| Melanoma stained with MART-1 antibody cocktail. | intelliPATH FLX | IP 077 G10 |
| CONCENTRATE | CM 077 A, B, C | |
| PREDILUTE | PM 077 AA, H | |
| CLONE | M2-7C10 + M2-9E3 | |
| DOWNLOADS | SOURCE | Mouse monoclonal |
| ISOTYPE | IgG2b + IgG2b | |
| ANTIGEN | MART-1 (Melan-A) | |
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