| ANTIBODY PHOTO | E-cadherin | |
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E-cadherin Description E-cadherin is a transmembrane glycoprotein that mediates epithelial cell-to-cell adhesion. The loss of E-cadherin can result in the disruption of cell clusters. It is therefore, postulated that E-cadherin may function as a tumor suppressor protein. The loss of E-cadherin has been associated with metastasis and poor prognosis in invasive breast cancer and can help differentiate between ductal and lobular neoplasms of the breast. It has also been shown to be an independent predictor in the disease progression in bladder cancer. |
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| PHOTO DESC. | Cat No. | |
| Breast cancer stained with E-cadherin. | intelliPATH FLX | IP 170 G10, G20 |
| CONCENTRATE | CM 170 A, B, C | |
| PREDILUTE | PM 170 AA | |
| CLONE | HECD-1 | |
| DOWNLOADS | SOURCE | Mouse monoclonal |
| ISOTYPE | IgG1 | |
| ANTIGEN | E-cadherin | |
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