| ANTIBODY PHOTO | Retinoblastoma | |
 |
Retinoblastoma Description 1F8 recognizes a 105 kDa phosphoprotein, identified as retinoblastoma (Rb) gene product. The epitope is localized between aa703-772 of human Rb protein. It shows no cross-reaction with p107 or p300. The retinoblastoma gene product has been shown to play a key role in cell cycle control and is known as a tumor suppressor gene. Loss of its function leads to tumor development. It is widely expressed in a variety of human tissues including mammary carcinoma, esophageal cancer, squamous cell carcinoma and cervical cancer. |
|
| PHOTO DESC. | Cat No. | |
| Squamous cell carcinoma stained with Retinoblastoma antibody. | intelliPATH FLX | N/A |
| CONCENTRATE | CM 211 A | |
| PREDILUTE | N/A | |
| CLONE | 1F8 | |
| DOWNLOADS | SOURCE | Mouse monoclonal |
| ISOTYPE | IgG1 | |
| ANTIGEN | Retinoblastoma | |
 |
||
