| ANTIBODY PHOTO | Kappa + Lambda Multiplex Stain Cocktail | |
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Kappa + Lambda Multiplex Stain Cocktail Description Kappa and lambda antibodies are usually run together on two separate tissues. In normal tissue, the kappa and lambda cell ratio is approximately 2:1. The double stain antibody allows the investigator to simultaneously see both kappa (M) (brown) and lambda (P) (red) on the same tissue section, thus allowing the end-user a more accurate and easier assessment of both stains. The double stain predilute must be used in conjunction with BIOCAREs MACH 2 Double Stain Detection Kit (DAB and Fast Red). The antibody cocktail recognizes both kappa and lambda light chains. It is reportedly useful in the identification of myelomas, plasmacytomas, and certain non-Hodgkins lymphomas. The most common feature of these malignancies is the restricted expression of a single light chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant. |
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| PHOTO DESC. | Cat No. | |
| Neoplastic lymphoma stained with Kappa + Lambda. | intelliPATH FLX | IP 214DS G10 |
| CONCENTRATE | N/A | |
| PREDILUTE | PPM 214DS AA, H | |
| CLONE | KDB-1 (kappa only) | |
| DOWNLOADS | SOURCE | Mouse monoclonal, Rabbit polyclonal |
| ISOTYPE | IgG1 (kappa only) | |
| ANTIGEN | Kappa and Lambda Light Chains | |
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