| ANTIBODY PHOTO | Pan Melanoma + Ki-67 | |
 |
Pan Melanoma + Ki-67 Description This multiplex stain can distinguish melanocytotic nevi that mimic melanoma. The multiplex application serves as a tool to identify the proliferation rate of melanocytic lesions in cases in which melanocytes are sparse, there are dense lymphocytic infiltrates and melanocytes are mixed with fibroblasts. In general, a higher proliferative fraction is seen in melanoma than in melanocytic nevi. There are many types of nevi, and some simulate melanoma closely. If the double stain shows a very low Ki-67 (DAB) labeling rate in MART-1/Tyrosinase positive cells (Fast Red), this favors benignity. A high rate, especially toward the deep part of a melanocytic lesion raises the possibility of malignancy. |
|
| PHOTO DESC. | Cat No. | |
| Melanoma stained with Pan Melanoma + Ki-67 cocktail. | intelliPATH FLX | N/A |
| CONCENTRATE | N/A | |
| PREDILUTE | PM 362 DS AA, H | |
| CLONE | M2-7C10 + M2-9E3 + T3-11 + SP6 | |
| DOWNLOADS | SOURCE | Mouse Monoclonal and Rabbit Monoclonal |
| ISOTYPE | IgG2a + IgG2b/kappa + IgG2b/kappa + rabbit IgG | |
| ANTIGEN | Melanoma / Ki-67 | |
 |
||
