| ANTIBODY PHOTO | p63-2X | |
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p63-2X Description p53 homologue p63 encodes for different isotypes able to either transactivate p53 reporter genes (TAp63) or act as p53-dominant negatives. p63 is detected in prostate basal cells in normal prostate, however, it is negative in malignant tumors of the prostate gland. Thus p63 is useful as a differential marker for benign and malignant tumors of prostate gland and can be used in a panel of antibodies such as HMW CK(34ßE12), PSA and PSAP. p63 may play a significant role in prostate development by maintaining a prostate stem cell population. Striated muscle staining may be observed with p63. p63 2X may be combined with an additional antibody to form a PIN Cocktail. |
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| PHOTO DESC. | Cat No. | |
| Prostate stained with p63-2X antibody. | intelliPATH FLX | N/A |
| CONCENTRATE | N/A | |
| PREDILUTE | PM 366 AAK, HK | |
| CLONE | BC4A4 | |
| DOWNLOADS | SOURCE | Mouse monoclonal |
| ISOTYPE | IgG 2a/kappa | |
| ANTIGEN | p63 | |
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