Biocare Products
Biocare Medical Double Vision Detection

Biocare Medical Multiplex Stains
Stains for multiple antibodies on a single slide

Biocare Medical Double Vision Multiple Stain System

Using the Multiplex staining system you can achieve remarkable multiple stain results like never seen before.

° Reduces the number of steps from 12-16 to 4-7 steps
° Avoids endogenous biotin blocking
° Processes 50+ percent less slides
° Has a turnaround time of less than two hours (4-step procedure)
° Is compatible with either manual or automated systems
° Needs less slides for interpretation

This new and innovative alkaline phosphatase (AP) and horseradish peroxidase (HRP) polymerization technology provides a significant increase in staining sensitivity when compared to other conventional AP or HRP conjugated secondary antibodies. It has been specially designed for a rapid double stain procedure and is suitable for most IHC automated stainers.

Biocare multiplex chromogenic and fluorescent systems are validated for multispectral imaging and image analysis. Click here for more information on CRi Nuance™ Multispectral Imaging systems.

Polymer Detection Kit #1 (4-Step)
(Mouse AP + Rabbit HRP)

Cat. No. Vol.
MRCT523G, H, L 6.0, 25, 100 ml

Polymer Detection Kit #2 (4-Step)
(Mouse HRP + Rabbit AP)

Cat. No. Vol.
MRCT525G, H, L 6.0, 25, 100 ml

MACH 2 Mouse Kits (for 7-Step)

Cat. No. Vol.
MHRP520 + MALP521 G, H, 6.0, 25 ml

Denaturing Solution
The 7-step kit is provided with a Denaturing Solution which prevents the second staining protocol from cross-reacting with the first. Denaturing Solution can also be purchased separately.

Cat. No. Vol.
DNS001H, L 25, 100 ml


Multiplex Stain Antibodies

Name intelliPATH FLX Predilute DATA SHEET Protocol / Kit
ADH-5 (Breast Marker Cocktail) N/A PM 360DS AA,H DATA SHEET Kit #2
CD10 + Cyclin D1 N/A PM 314DS AA DATA SHEET Kit #1
CD23 + CD5 N/A PM 315DS AA DATA SHEET Kit #1
CD56 + Synaptophysin N/A PPM 316DS AA DATA SHEET Kit #2
CDX2 + CK7 N/A PPM 338DS AA DATA SHEET Kit #2
CK5 + p63 with CK8/18 N/A PM 228DS AA DATA SHEET MACH 2 Mouse
CK5/6 + Calretinin N/A PM 246DS AA DATA SHEET Kit #2
D2-40 and CD34 N/A PM 272DS AA DATA SHEET MACH 2 Mouse
GCDFP-15 + Mammaglobin N/A PM 317DS AA DATA SHEET Kit #2
HMW CK and LMW CK N/A PM 245DS AA DATA SHEET MACH 2 Mouse (7 step)
Ki-67 + Caspase-3 N/A PPM 240DS AA DATA SHEET Kit #2
Kappa + Lambda N/A PPM 214DS AA DATA SHEET Kit #2
L26 + CD3 N/A PM 237DS AA DATA SHEET Kit #1
Pan Melanoma + Ki-67 N/A PM 362DS AA DATA SHEET Kit #2
Pan Melanoma + S100 (Tyrosinase + MART-1 + S100 ) N/A PPM 213DS AA DATA SHEET Kit #2
PIN-4 (CK5 + CK14 + p63 + P504S) IP 225DS G10, G20 PPM 225DS AA ASR / RUO Kit #2

For more comprehensive information about Multiplex Stain Antibodies, see the antibody section of this website.